https://journal.unismuh.ac.id/index.php/aimj/issue/feedAl-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran2024-03-23T13:56:13+07:00Juliani Ibrahimjuliabox1@gmail.comOpen Journal Systemshttps://journal.unismuh.ac.id/index.php/aimj/article/view/9984CORRELATION OF C-REACTIVE PROTEIN (CRP), AND INTERLEUKIN-6 (IL-6) WITH HEPCIDIN LEVELS IN PATIENTS WITH ANEMIA OF CHRONIC DISEASE (ACD)2024-01-27T18:23:44+07:00I Putu Arya Giri Prebawaputu.aryagiri@gmail.comKetut Suegaksuega@yahoo.com<p><em>Anemia of chronic disease (ACD) or anemia of chronic inflammation is the most common cause of anemia in hospitalized patients. Recent studies revealed that interleukin-6 (IL-6), C-reactive protein (CRP), and Hepcidin play a key role in ACD pathogenesis. This study is an observational study with a crossectional approach that aims to see the relationship between levels of inflammatory marker such as CRP and IL-6 with Hepcidin on the incidence of ACD at Prof Ngoerah Hospital Denpasar. This study involved 92 samples. Descriptive analysis will be presented in the form of tables and narratives for all data obtained in this study. Bivariate analysis was carried out using the Spearman correlation. The mean CRP level of the patients in this study was 89.1 ± 80.1 mg/L which could be categorized as high. The mean Il-6 level of the patients in this study was 91,8±88,4 pg/mL which could be categorized as high and the Hepcidin level in this study was 64.4 ± 49.9 ng/dL. This study shows that inflammation plays a role in increasing levels of Hepcidin which plays a role in the pathogenesis of ACD. This can be seen from the significant positive correlation between Hepcidin levels and IL-6 levels (P=0,00), although there is no correlation between Hepcidin and CRP. Inflammation plays a role in increasing levels of Hepsidin which plays a role in the pathogenesis of ACD.</em></p>2023-08-31T13:35:55+07:00Copyright (c) 2023 I Putu Arya Giri Prebawa, Ketut Suegahttps://journal.unismuh.ac.id/index.php/aimj/article/view/10722ANALISIS KARAKTERISTIK IBU DAN KONDISI KEHAMILAN YANG BERHUBUNGAN DENGAN KEJADIAN INTRA UTERINE FETAL DEATH (IUFD)2024-01-27T18:23:44+07:00Aulia Zulfiana Nur Faizaauliazulfi13@gmail.comMuhamad Taufiqy Setyabudidr.taufiqy1@gmail.comKanti Ratnaningrumkantiratna@unimus.ac.id<p><em>Intra Uterine Fetal Death (IUFD) is still the cause of the increase in Neonate Death (AKN) and Baby Death (AKB) numbers in Indonesia. IUFD events can be caused by fetal factors, maternal factors, or placental factors. Several previous studies have analyzed the incidence factors of IUFD separately and still rarely studies that analyze several variations of IUFD risk factors reviewed from fetal and mother conditions simultaneously, therefore researchers want to know the relationship between parity, maternal age, pregnancy anemia, preeclampsia, and IUGR with the incidence of Intra Uterine Fetal Death (IUFD). Research is observational analytics with cross-sectional approaches and total sampling techniques. Data retrieval is conducted at Tugurejo Semarang Hospital. The research data was taken from secondary medical record data of pregnant women who experienced IUFDs from January 2018 - December 2021. Analysis of this research data using the Fisher Exact Test test. In this study, there was a link between parity, maternal age, pregnancy anemia, preeclampsia, and IUGR (p=0.033; p=0.037; p=0.016; p 0.010; p 0.000) with IUFD events.</em></p>2023-08-31T13:35:55+07:00Copyright (c) 2023 Aulia Zulfiana Nur Faiza, Muhamad Taufiqy Setyabudi, Kanti Ratnaningrumhttps://journal.unismuh.ac.id/index.php/aimj/article/view/10925PENGARUH VARIASI KONSENTRASI MEDIUM PERTUMBUHAN DAN IDENTIFIKASI BAKTERI PEMBENTUK BIOFILM ORAL2024-01-27T18:30:51+07:00Asni Asni Aminasni.amin@umi.ac.idRusli rusli Ruslirusli.rusli@umi.ac.idAqilah Alviola Bani15020190082@umi.ac.id<em>Biofilm oral merupakan sekumpulan mikroorganisme baik bakteri, jamur ataupun kapang yang melekat di permukaan rongga mulut (gigi, lidah, langit-langit mulut, dan gusi) dan dibungkus oleh karbohidrat. Beberapa jenis bakteri pembentuk biofilm oral pencetus terbentuknya karang gigi bahkan karies gigi. Tujuan penelitian ini adalah untuk menentukan konsentrasi media tumbuh bakteri oral dan mengidentifikasi bakteri pembentuk biofilm oral. Metode penelitian menggunakan design experimental laboratorium kualitatif, terhadap bakteri oral pembentuk biofilm yaitu bakteri Fusobacterium nucleate (FN), Porphyromonas gingivalis (PG), dan Streptococcus mutans (SM). Bakteri ditumbuhkan pada media selektif Brucella Blood Agar (BBA) dengan penambahan darah domba (sheep blood) tidak terkoagulasi dengan variasi konsentrasi 5 dan 10% dalam kondisi anaerob. Bakteri yang tumbuh diidentifikasi bentuk morfologi dan pewarnaan Gram. Hasil penumbuhan bakteri pada media Brucella Blood Agar (BBA) dengan darah domba tidak terkoagulasi (DDTK) konsentrasi 5% menunjukkan bahwa bakteri FN tidak mengalami pertumbuhan, sedangkan bakteri PG dan SM dapat tumbuh. Pada konsentrasi media BBA 10% ketiga bakteri dapat tumbuh. Hasil identifikasi dengan pewarnaan Gram menunjukkan bakteri FN dan PG termasuk bakteri Gram negatif dengan sel berwarna merah muda. Sedangkan pada bakteri SM termasuk bakteri Gram positif yang menunjukkan warna biru pada selnya. Adapun bentuk morfologi sel bakteri PG berbentuk coccobasil, bakteri FN berbentuk basil dan SM berbentuk coccus. Konsentrasi media yang terbaik bagi penumbuhan bakteri Gram negatif (FN dan PG) dan bakteri Gram positif (SM) pembentuk biofilm oral adalah media yang konsentrasinya 10%</em>2023-08-31T13:35:55+07:00Copyright (c) 2023 Asni Asni Amin, Rusli rusli Rusli, Aqilah Alviola Banihttps://journal.unismuh.ac.id/index.php/aimj/article/view/10951ARTIFICIAL INTELLIGENCE IN OPHTHALMOLOGY: CHALLENGES AND READINESS IN INDONESIA2024-01-27T18:23:44+07:00Asnhy Anggun Dien Putriasnhy_a@yahoo.co.idIvana Beatrice Albertaivanabeatricealberta@gmail.comFredy Ciputrafredyciputra@gmail.com<p>Artificial Intelligence (AI) has been increasingly used in various fields of medicine. It involves the development of algorithms and computer programs that can learn from and adapt to data, enabling machines to perform tasks without explicit human instructions. The ultimate goal of AI is to create machines that can think and reason like humans. AI has the potential to transform the field of ophthalmology, which leads to improved patient care. This study aims to examine the current state of AI in ophthalmology, the challenges facing its adoption in Indonesia, and the opportunities for growth and development in this field.<strong> </strong>A literature search was conducted using PubMed, Google Scholar, and Proquest to identify relevant studies and reports related to AI in ophthalmology. AI in ophthalmology has been studied extensively in the field of screening, diagnosis, management, and predicting outcomes. Some studies proved that AI has a relatively high accuracy in diagnosing certain eye diseases, as demonstrated by its high sensitivity and specificity. However, high accuracy does not necessarily mean that AI is ready for clinical practice, especially in Indonesia. Several challenges include the risk of bias, the absence of standard assessment methods for AI, inadequate infrastructure and regulation, ethics, and sociocultural aspects. AI has the potential to revolutionize the ophthalmology field in Indonesia, leading to better patient outcomes and more efficient healthcare systems.</p>2023-08-31T13:35:55+07:00Copyright (c) 2023 Asnhy Anggun Dien Putri, Ivana Beatrice Alberta, Fredy Ciputrahttps://journal.unismuh.ac.id/index.php/aimj/article/view/11573LEVEL OF KNOWLEDGE, INDIVIDUAL CHARACTERISTICS AND ANTIBIOTIC CONSUMPTION BEHAVIOR AT TANAKARAENG VILLAGE, GOWA, INDONESIA2024-01-27T18:23:44+07:00Bramantyas Kusuma Hapsaribramantyas.sari@med.unismuh.ac.idAaliyah Pryanditha Maharaniaaliyahpryanditha@med.unismuh.ac.idAndi Tenri Padadtenripadad@gmail.com<p>Overuse or inappropriate antibiotics can cause resistance so that the genetic ability of bacteria become less or not sensitive to antibiotics through resistance mechanisms acquired, spontaneous mutation, and transferred resistance. However, if society have not changed the way they consume or use antibiotics rational, new antibiotics also will the same with now and be ineffective. Knowing the distribution of knowledge levels, individual characteristics, and behavior consumption antibiotics in society rural. This research is a <em>cross sectional study. </em>Questionnaire used to get information knowledge , characteristics and behavior consumption antibiotics in society Village Tanakaraeng Regency Gowa , South Sulawesi, Indonesia. A total of 124 respondents were involved in study this . There is 74 respondent (59.7%) from group age 20 – 35 years old, majority woman that is 91 respondent (73.4%) with complaint main most sick of tooth and headache that is 25 respondent (20.2%). Place purchase antibiotics the most is pharmacy with 62 respondent (50%), majority from college is 43 respondent (34.7%). There is 70 respondent (56.5%) with good knowledge. Based on behavior consumption antibiotics there is 110 respondents (88.7%) that have behavior irrational. The people of Tanakaraeng Village already have good knowledge about antibiotics, but majority own behavior irrational in consuming antibiotics</p>2023-09-19T00:00:00+07:00Copyright (c) 2023 Bramantyas Kusuma Hapsari, Aaliyah Pryanditha Maharani, Andi Tenri Padadhttps://journal.unismuh.ac.id/index.php/aimj/article/view/11101PEMERIKSAAN PENUNJANG LIKEN AMILOIDOSIS2024-03-23T13:54:50+07:00Sukma Cukey Anjayanicukeyponk@gmail.comAndi Salsa Anggerainiandisalsaanggeraini@gmail.comNelly Nellynelly@gmail.comNur Faidahnurfaidah@gmail.com<p><em>Lichen amyloidosis (LA) is a disease caused by amyloid deposits in the dermis which is chronic, localized and very itchy. LA is characterized by the presence of discretely scattered hyperpigmented and hyperkeratotic papules, which can coalesce to form verrucous plaques, present in the extensor area of the arms and legs. The pathogenesis of LA is unclear, but suspected that there is reactivity between antikeratin antibodies and amyloid deposits in the skin. </em><em>Several examination that can be used to make diagnose LA, such as histopathology (hematoxylin-eosin staining and congo-red) and immunofluorescence (IgM, C3, IgA deposits in the basement membrane area). This paper will discuss further about several examinations that can be used to the diagnosis of LA.</em></p>2023-08-31T13:35:55+07:00Copyright (c) 2023 sukma cukey anjayanihttps://journal.unismuh.ac.id/index.php/aimj/article/view/10953CURRENT MANAGEMENT OF POLYPOIDAL CHOROIDAL VASCULOPATHY2024-01-27T18:23:44+07:00Fredy Ciputrafredyciputra@gmail.com<p>Currently, there are several treatment options that can be offered to patients with PCV, including photodynamic therapy, administration of anti-vascular endothelial growth factor (anti-VEGF) agents, thermal laser, or a combination of these. Currently, PDT has the highest potential as it is a therapeutic option targeted at the choroid. Although PDT has been recognized as the standard treatment for PCV due to its high regression rate and good functional outcomes, it also has some disadvantages. Initially, PDT treatment for PCV was found to have complications such as acute vision loss and massive subretinal haemorrhage. These complications have been reduced with the introduction of anti-VEGF agents in PCV management. There is no specific anti-VEGF agent that has shown superiority over others. Thermal laser is an effective and relatively cheaper modality of treatment compared to PDT. Thermal laser plays an important role in the management of PCV in extrafoveal, peripapillary, and peripheral areas. Combination therapy is an attractive option for patients with PCV which can provide better polyp closure and visual outcomes, and also a decrease in complication rates compared to monotherapy.</p>2023-08-31T13:35:55+07:00Copyright (c) 2023 Fredy Ciputrahttps://journal.unismuh.ac.id/index.php/aimj/article/view/9732CARDIORENAL SYNDROME: NARRATIVE REVIEW2024-01-27T18:23:44+07:00Sidhi Laksonosidhilaksono@uhamka.ac.idDhiki Nugrahadhikin@gmail.comCardiorenal syndrome is a disorder that involves the heart and kidneys, acute or chronic dysfunction of one organ can induce acute or chronic dysfunction of other organs. Renal dysfunction associated with acute heart failure, and vice versa, causes considerable morbidity and mortality. Until recently, there has been no consistent and effective strategy in the management of patients with cardiorenal syndrome. Generally, only done by reducing the volume of fluid so as not to worsen kidney function. Early identification leads to more effective treatment and shorter hospitalization. A multidisciplinary approach involving cardiologists and renal specialists is essential.2023-08-31T13:35:55+07:00Copyright (c) 2023 Sidhi Laksono, Dhiki Nugrahahttps://journal.unismuh.ac.id/index.php/aimj/article/view/11104NEKROLISIS EPIDERMAL TOKSIK (NET) YANG DICURIGAI KARENA OBAT PELANGSING: Laporan satu kasus2024-03-23T13:56:13+07:00Sukma Cukey Anjayanicukeyponk@gmail.comNur Rahmah Shaleh Matharyeyennurrahmah79@gmail.com<p><em>Toxic Epidermal Necrolysis is a rare life-threatening skin disorder, with severe loss of epidermis and mucous membrane involvement. Most often caused by secondary drug use. A case of toxic epidermal necrolysis in 29 years 29-year-old woman. Probable was caused by a slimming drug. The treatment was a systemic corticosteroid. The treatment gives an improvement.</em></p>2023-08-31T13:35:55+07:00Copyright (c) 2023 sukma cukey anjayani, Nur Rahmah Shaleh Mathar